Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand

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Abstract

Retrospective case series from Thailand have reported the presence of intra-abdominal abscesses in around half of patients with melioidosis, a much higher rate than our clinical experience would suggest. We performed a prospective, observational study of 230 adult patients with culture-confirmed melioidosis in which all patients underwent abdominal ultrasound. One or more abscesses were detected in the liver and/or spleen in 77 (33%) cases. These were often multiple (70%, 31/44 in hepatic abscesses and 88%, 50/57 in splenic abscesses) and clinically silent (27% of cases with abscesses presenting with abdominal pain). The mortality rate at 4 weeks post-discharge was lower in patients who were abscess-positive vs abscess-negative (10%, 8/77 vs 20%, 31/153). © 2012 Royal Society of Tropical Medicine and Hygiene.

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Maude, R. R., Vatcharapreechasakul, T., Ariyaprasert, P., Maude, R. J., Hongsuwan, M., Yuentrakul, P., … Peacock, S. J. (2012). Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand. Transactions of the Royal Society of Tropical Medicine and Hygiene, 106(10), 629–631. https://doi.org/10.1016/j.trstmh.2012.05.007

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