Proteobacteria: Microbial signature of dysbiosis in gut microbiota

287Citations
Citations of this article
442Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Recent advances in sequencing techniques, applied to the study of microbial communities, have provided compelling evidence that the mammalian intestinal tract harbors a complex microbial community whose composition is a critical determinant of host health in the context of metabolism and inflammation. Given that an imbalanced gut microbiota often arises from a sustained increase in abundance of the phylum Proteobacteria, the natural human gut flora normally contains only a minor proportion of this phylum. Here, we review studies that explored the association between an abnormal expansion of Proteobacteria and a compromised ability to maintain a balanced gut microbial community. We also propose that an increased prevalence of Proteobacteria is a potential diagnostic signature of dysbiosis and risk of disease.

Author supplied keywords

Cite

CITATION STYLE

APA

Shin, N. R., Whon, T. W., & Bae, J. W. (2015, September 1). Proteobacteria: Microbial signature of dysbiosis in gut microbiota. Trends in Biotechnology. Elsevier Ltd. https://doi.org/10.1016/j.tibtech.2015.06.011

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free