Quantification of virus particles using nanopore-based resistive-pulse sensing techniques

75Citations
Citations of this article
147Readers
Mendeley users who have this article in their library.

Abstract

Viruses have drawn much attention in recent years due to increased recognition of their important roles in virology, immunology, clinical diagnosis, and therapy. Because the biological and physical properties of viruses significantly impact their applications, quantitative detection of individual virus particles has become a critical issue. However, due to various inherent limitations of conventional enumeration techniques such as infectious titer assays, immunological assays, and electron microscopic observation, this issue remains challenging. Thanks to significant advances in nanotechnology, nanostructure-based electrical sensors have emerged as promising platforms for real-time, sensitive detection of numerous bioanalytes. In this paper, we review recent progress in nanopore-based electrical sensing, with particular emphasis on the application of this technique to the quantification of virus particles. Our aim is to provide insights into this novel nanosensor technology, and highlight its ability to enhance current understanding of a variety of viruses.

Cite

CITATION STYLE

APA

Yang, L., & Yamamoto, T. (2016, September 22). Quantification of virus particles using nanopore-based resistive-pulse sensing techniques. Frontiers in Microbiology. Frontiers Media S.A. https://doi.org/10.3389/fmicb.2016.01500

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free