Radiation therapy for palliation of sarcoma metastases: A unique and uniform hypofractionation experience

10Citations
Citations of this article
17Readers
Mendeley users who have this article in their library.

Abstract

Radiotherapy (RT) is our preferred modality for local palliation of metastatic soft tissue sarcoma (STS). A short and intense course of RT is usually needed for rapid palliation and local control of metastatic disease. Seventeen patients at a median age of 61 had symptomatic metastatic sarcoma and required rapid palliation. The symptoms related to the metastases were either pain or discomfort. All patients were treated by a short and intensive course of administration: 39 Gy were given in 13 fractions of 3 Gy/day, 5 times a week. Median follow-up period was 25 weeks. The treatment was well tolerated. Acute side effects included grade one skin toxicity. No wound complications were noted among those undergoing surgery. Late side effects included skin pigmentation and induration of irradiated soft tissues. Durable pain control was achieved in 12 out 15 cases treated for gross metastases. Tumor progression was seen in the 3 other cases within a period of two to nine months. Among 5 lesions which were irradiated as an adjunctive treatment following resection, no local recurrence was observed. The results of this series, although limited in size, point to the safety and feasibility of hypofractionated RT for palliation of musculoskeletal metastases from sarcoma. © 2010 Viacheslav Soyfer et al.

Cite

CITATION STYLE

APA

Soyfer, V., Corn, B. W., Kollender, Y., Tempelhoff, H., Meller, I., & Merimsky, O. (2010). Radiation therapy for palliation of sarcoma metastases: A unique and uniform hypofractionation experience. Sarcoma, 2010. https://doi.org/10.1155/2010/927972

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free