BACKGROUND: A 21-year-old female patient had chorioretinitis in the left eye which relapsed while being on anti-tubercular treatment and oral corticosteroids leading to blindness and the loss of the left eye.<br /><br />FINDINGS: Mycobacterium tuberculosis causing chorioretinitis showed a poor response, and the lung lesions showed a good response to the same anti-tubercular treatment.<br /><br />CONCLUSIONS: Mycobacterium tubercle bacilli in the eye may show a poor response to the anti-tubercular drugs due to poor ocular penetration of the drugs secondary to early ocular hypoxia.
Agarwal, M., Jha, V., & Biswas, J. (2014). Rapidly blinding posterior tubercular uveitis. Journal of Ophthalmic Inflammation and Infection, 4(1). https://doi.org/10.1186/1869-5760-4-13