A common requirement of statistical methods, critical to the interpretation of the data, is that the analyzed observations are independent. This is not always the case in experiments and clinical studies, a mistake which can be expected to lead to erroneous study results. The phenomenon is explained, its consequences described, and suggestions to avoid the problems presented. © 2012 Osteoarthritis Research Society International.
Ranstam, J. (2012, June). Repeated measurements, bilateral observations and pseudoreplicates, why does it matter? Osteoarthritis and Cartilage, 20(6), 473–475. https://doi.org/10.1016/j.joca.2012.02.011