In this issue, Skerker et al. (2008) present a rational method for rewiring the protein-protein interactions and output responses of prokaryotic two-component signal transduction systems. This work has important implications for understanding the specificity of protein interactions and for designing protein-based synthetic signaling cascades. © 2008 Elsevier Inc. All rights reserved.
Kohanski, M. A., & Collins, J. J. (2008, June 13). Rewiring Bacteria, Two Components at a Time. Cell. https://doi.org/10.1016/j.cell.2008.05.035