Rod-like cholesterol micelles in aqueous solution studied using polarized and depolarized dynamic light scattering

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Abstract

Micelles of cholesterol in aqueous solution have been investigated using polarized and depolarized dynamic light scattering. They are shown to be highly extended and characterized by a narrow size distribution. It is shown that a rod-like model is applicable with length, L = 580 nm. Determination of the rotational diffusion coefficient by analysis of the autocorrelation function gave a value of theta = 150 s-1, which is close to the calculated value for the rod with this dimension. Depolarized dynamic light scattering measurements as a function of angle gave a value of 110 s-1. © 1992, The Biophysical Society. All rights reserved.

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Castanho, M. A., Brown, W., & Prieto, M. J. (1992). Rod-like cholesterol micelles in aqueous solution studied using polarized and depolarized dynamic light scattering. Biophysical Journal, 63(6), 1455–1461. https://doi.org/10.1016/S0006-3495(92)81733-2

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