Role of amiodarone in reducing atrial fibrillation after cardiac surgery in adults

Abstract

Atrial fibrillation is a common occurrence after cardiac surgery and the source of financial expenditure and complications. A critical literature review was undertaken to examine the use of amiodarone therapy to prevent or manage atrial fibrillation after cardiac surgery. Evidence strongly suggests that perioperative treatment of cardiac patients with amiodarone may reduce the incidence of atrial fibrillation with minimal adverse effects. Further study is warranted to determine the optimal timing and dosing, for the drug's most cost-effective use. © 2002 by The Society of Thoracic Surgeons.