Role of PET-CT in the assessment of myocardial viability in patients with left ventricular dysfunction

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Abstract

Aim Role of PET-CT in assessment of myocardial viability in patients with LV dysfunction. Methods This prospective study included 120 patients with LV dysfunction who underwent 99mTechnetium-Sestamibi myocardial perfusion SPECT-CT and 18FFDG cardiac PET-CT. They also underwent serial echocardiography and coronary angiography along with myocardial perfusion and FDG PET study. Results Thirty-three patients had single vessel disease, 48 had triple vessel disease, and rest had double vessel disease. Among 786 segments, matched defects were seen in 432 (55%) and mismatched defects in 354 (45%) segments. 78 patients were surgically managed, and 42 were medically managed. The change in LVEF after surgical management was statistically significant compared to medical management. Conclusion Viability assessment should be performed in patients who present after 12 h of acute myocardial infarction or with LV dysfunction due to ischemic heart disease to decide upon appropriate surgical management.

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Srivatsava, M. K., Indirani, M., Sathyamurthy, I., Sengottuvelu, G., Jain, A. S., & Shelley, S. (2016). Role of PET-CT in the assessment of myocardial viability in patients with left ventricular dysfunction. Indian Heart Journal, 68(5), 693–699. https://doi.org/10.1016/j.ihj.2015.11.017

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