Objectives: The aim of this study was to assess the role of anaerobic threshold (AT) in cardiopulmonary exercise testing (CPET) as an independent predictor of outcome in patients undergoing Abdominal aortic aneurysm (AAA) repair. Methods: Analysis of a prospectively collected database of patients recruited in a randomised controlled trial for pre-operative risk assessments of elective AAA repair patients. Peri-operative parameters & outcomes were recorded for all patients. Primary end point was 30 day mortality. Intergroup analysis (alive vs. dead) was performed using SPSS 16.0. Results: 30 patients [26 men, median age 75 years (IQR: 68-78)] were included in the study. Median Anaerobic threshold was 12.67 ml/min/kg (IQR: 8.6-16.42). Median hospital stay was 7 days (IQR: 5-12), post operative complications were observed in 10% (n=3) and mortality rate was 7% (n=2). Inter-group Analysis: There was a significant difference (P=0.042) between the two groups in the AT [median AT, Alive: 12.76 ml/min/kg (range; 5.52-22.37), Dead: 6.67 ml/min/kg (range; 6.08-7.26)]. However, there was no statistically significant difference between the two groups for basic demographics, co-morbidities and pre-operative medications. Conclusions: Anaerobic threshold in cardiopulmonary exercise testing may be used as an independent predictor of outcome in patients undergoing AAA repair. Further studies are required to establish its role as an independent predictor of morbidity & mortality in elective AAA patients.
Khan, J. A., Mazari, F. A., Samuel, N., Smith, G., Gohil, R., Chetter, I., & McCollum, P. (2011). RR24. Assessment of Anaerobic Threshold in Cardiopulmonary Exercise Testing as an Independent Predictor of Outcome in Patients Undergoing Abdominal Aortic Aneurysm (AAA) repair. Journal of Vascular Surgery, 53(6), 108S-109S. https://doi.org/10.1016/j.jvs.2011.03.210