Screening preterm children for autism at 2 years of age

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Comments on an article by A. Guy et al. (see record 2015-04778-025), who published a screening study of children born preterm using the Modified Checklist for Autism in Toddlers (M-CHAT) questionnaire at age 2 years. The study by Guy et al had some similarities to the current authors' study, such as age of screening (2 years, age corrected), comparable rates of return of questionnaires in the preterm cohort (58% vs 63.6%), and similar M-CHAT positivity (14.5% vs 17.8%). However, the prevalence of autism was discrepant between the studies (2.4% vs 9.7%). In the commentary authors' opinion, the most plausible explanation is that the use of a battery of three screening tests diminished the rate of false negative screening results. Another reason for the difference may have been different inclusion criteria. An additional, although speculative, explanation could be that the followup telephone interview was overly restrictive with regard to M-CHAT positivity. (PsycINFO Database Record (c) 2015 APA, all rights reserved).




Hrdlicka, M., & Dudova, I. (2015, July 1). Screening preterm children for autism at 2 years of age. Journal of Pediatrics. Mosby Inc.

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