Self-assembled nanowires of diphenylalanine and graphene (FF-G) nanocomposites have been prepared in aqueous solution by a simple one-step method. Hemoglobin (Hb) as a model molecule is further immobilized on the FF-G nanocomposites in order to construct a H2O2amperometric biosensor. According to UV–vis spectroscopy, the immobilized Hb, overall retains its original structure and the bioactivity. Systematic electrochemical tests demonstrate that the Hb/FF-G modified glassy carbon electrode shows high electrocatalytic activity to H2O2. The biosensor exhibits a wide linear response in the range from 5.0 × 10−7to 5.0 × 10−4mol L−1, with a low detection limit of 1.0 × 10−7mol L−1. Our results indicate that the nanowires of FF-G nanocomposites obtained in a facile method are promising for application in electrochemical biosensors due to its excellent biocompatibility and good charge-transfer ability.
Wu, Y., Wang, F., Lu, K., Lv, M., & Zhao, Y. (2017). Self-assembled dipeptide-graphene nanostructures onto an electrode surface for highly sensitive amperometric hydrogen peroxide biosensors. Sensors and Actuators, B: Chemical, 244, 1022–1030. https://doi.org/10.1016/j.snb.2017.01.048