In this issue of Molecular Cell, Skourti-Stathaki et al. (2011) report that human Senataxin, like its yeast homolog Sen1, promotes termination by RNA polymerase II and resolves RNA/DNA duplexes formed during transcription. Their results may help uncover a cause of motor neuron degeneration. © 2011 Elsevier Inc.
Brow, D. A. (2011, June 24). Sen-sing RNA Terminators. Molecular Cell. https://doi.org/10.1016/j.molcel.2011.06.002