Simultaneous detection of biomolecular interactions and surface topography using photonic force microscopy

3Citations
Citations of this article
14Readers
Mendeley users who have this article in their library.

Abstract

We developed a photonic force microscope that can map multiple parameters simultaneously, including the surface topography and biomolecular interactions. To track the position of the probe bead and to determine contact position with the sample surface, we adopted a video analysis method using the diffraction pattern of monochromatic light passing through the probe bead. To demonstrate the capability of the microscope, we report the simultaneous measurement of the molecule distribution of DNA oligonucleotides on the surface, the binding strength of DNA hybridization between the bead and surface, and the topography of the smooth molded surface. © 2012 Elsevier B.V.

Cite

CITATION STYLE

APA

Heo, S., Kim, K., Christophe, R., Yoon, T. Y., & Cho, Y. H. (2013). Simultaneous detection of biomolecular interactions and surface topography using photonic force microscopy. Biosensors and Bioelectronics, 42(1), 106–111. https://doi.org/10.1016/j.bios.2012.10.049

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free