In this issue of Chemistry & Biology, Duckmanton et al.  have rigorously studied myotube fragmentation, or "cellularization," triggered by microtubule-disrupting agents. They convincingly demonstrate that cellularization remains integral to myogenic dedifferentiation, but is insufficient for reentry of the mononucleate progeny into the cell cycle. ©2005 Elsevier Ltd All rights reserved.
Hines, J. (2005, October). Small molecules driving myotube fission. Chemistry and Biology. https://doi.org/10.1016/j.chembiol.2005.10.001