In this paper, hydroxyapatite-carbon nanotube/titania (HA-CNT/TiO 2 ) double layer coatings were successfully developed on titanium (Ti) supstrates intended for biomedical applications. A TiO 2 coating was firstly developed by anodization to improve bonding between HA and Ti, and then the layer of HA and CNTs was coated on the surface by the sol-gel process to improve the biocompatibility and mechanical properties of Ti. The surfaces of double layer coatings were uniform and crack-free with a thickness of about 7 μm. The bonding strength of the HA-CNT/TiO 2 coating was higher than that of the pure HA and HA-CNT coatings. Additionally, in vitro cell experiments showed that CNTs promoted the adhesion of preosteoblasts on the HA-CNT/TiO 2 double layer coatings. These unique surfaces combined with the osteoconductive properties of HA exhibited the excellent mechanical properties of CNTs. Therefore, the developed HA-CNT/TiO 2 coatings on Ti supstrates might be a promising material for bone replacement. © 2012 by the authors; licensee MDPI.
Ji, X., Lou, W., Wang, Q., Ma, J., Xu, H., Bai, Q., … Liu, J. (2012). Sol-gel-derived hydroxyapatite-carbon nanotube/titania coatings on titanium supstrates. International Journal of Molecular Sciences, 13(4), 5242–5253. https://doi.org/10.3390/ijms13045242