Spilanthol: Occurrence, extraction, chemistry and biological activities

Citations of this article
Mendeley users who have this article in their library.


Spilanthol (C 14 H 23 NO, 221.339 g/mol) is a bioactive compound that is found in many different plants that are used as traditional remedies throughout the world. It is present in Heliopsis longipes and several species in the genus Acmella, including A. oleracea L., also known as paracress and jambu. Its leaves and flowers have sensory properties (pungency, tingling, numbing, mouth-watering) that make it a popular spice and ingredient in several Brazilian dishes. Spilanthol can exert a variety of biological and pharmacological effects including analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial, antilarvicidal and insecticidal activities. So, the aim of this review is to present a literature review on the spilanthol that describes its occurrence, chemistry, extraction and biological activities.




Barbosa, A. F., de Carvalho, M. G., Smith, R. E., & Sabaa-Srur, A. U. O. (2016, January 1). Spilanthol: Occurrence, extraction, chemistry and biological activities. Brazilian Journal of Pharmacognosy. Sociedade Brasileira de Farmacognosia. https://doi.org/10.1016/j.bjp.2015.07.024

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free