Spontaneous regression of primary progressive Hodgkin's lymphoma in a pediatric patient: A case report and review of literature

Abstract

Spontaneous regression of malignancies is a very rare phenomenon. Our research of existing literature yielded only 16 cases of Hodgkin's lymphoma which regressed spontaneously. The outcome of primary progressive Hodgkin's lymphoma is poor even with salvage chemotherapy and autologous bone marrow transplantation. Here we present a case of primary progressive Hodgkin's lymphoma, which regressed spontaneously after failure of salvage chemotherapy. To our knowledge, this is the first case report of primary progressive Hodgkin's lymphoma undergoing spontaneous regression. © 2013 King Faisal Specialist Hospital and Research Centre. Published by Elsevier Ltd. All rights reserved.