Stem cell niches: Famished paneth cells, gluttonous stem cells

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Abstract

Adult tissue stem cells adjust to environmental changes. A new study in the mouse intestine reveals that caloric restriction causes Paneth cells to repress mTORC1 signaling; this in turn stimulates proliferation of neighboring stem cells. © 2012 Elsevier Ltd.

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Kim, T. H., & Shivdasani, R. A. (2012, July 24). Stem cell niches: Famished paneth cells, gluttonous stem cells. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2012.06.017

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