Structural characterization and hypolipidemic activity of a polysaccharide PGEB-3H from the fruiting bodies of gastrodia elata blume

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Abstract

The purified Gastrodia elata Blume polysaccharide (PGEB-3H), was found to be a glucan with a molecular weight of 28.8 kDa and specific rotation of +206.3 (ca.0.003, H2O). The structural characterics of PGEB was investigated by chemical methods (partial hydrolysis with acid, methylation reaction, periodate oxidation, and Smith degradation) and instrument analysis (IR and NMR). PGEB-3H was mainly composed by glucose, and had a (1→4)-α-D- glucan main chain occasionally branched with a-1,6 glycosidic linkage. PGEB-3H exhibited potential lipid-lowering effects in hyperlipidemia rats. © 2012 Published by Elsevier Ltd.

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Ming, J., Liu, J., Wu, S., Guo, X., Chen, Z., & Zhao, G. (2012). Structural characterization and hypolipidemic activity of a polysaccharide PGEB-3H from the fruiting bodies of gastrodia elata blume. In Procedia Engineering (Vol. 37, pp. 169–173). Elsevier Ltd. https://doi.org/10.1016/j.proeng.2012.04.221

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