A recent meeting to evaluate the state of the art of protein structure prediction saw progress on all fronts; for prediction methods based on comparative modeling or fold recognition, the progress was incremental, but in the case of ab initio structure prediction, some surprising successes were reported.
Shortle, D. (1999, March 25). Structure prediction: The state of the art. Current Biology. Current Biology Ltd. https://doi.org/10.1016/S0960-9822(99)80130-4