This study sought to analyze the molecular mechanisms contributing to the development of rifaximin (Rfx) resistance in vitro in Escherichia coli. Twenty-eight Rfx-resistant mutants as well as four clinical isolates of E. coli were analyzed. The results obtained show that mutations in the rpoB gene and overexpression of Phe-Arg-β-naphthylamide (PAβN)-inhibitible efflux pump were implicated in Rfx resistance.
Fernanda Alves Dorella, D. R., & Thiago Luiz de Paula Castro, L. G. C. P. (2013). Subclinical Diagnosis of Caseous Lymphadenitis Based on ELISA in Sheep from Brazil. Journal of Bacteriology & Parasitology, 04(03). https://doi.org/10.4172/2155-9597.1000170