The subcutaneous blood flow (SBF) was measured by the133Xe washout method in the scalp of 14 patients with early male pattern baldness. Control experiments were performed in 14 normal haired men matched for age. The SBF in the scalp of the normal individuals was about 10 times higher than previously reported SBF values in other anatomical regions. In patients with early male pattern baldness, SBF was 2.6 times lower than the values found in the normal individuals (13.7 ±9.6 vs 35.7 ±10.5 ml/100 g/min-1). This difference was statistically significant (p ≪ 0.001). A reduced nutritive blood flow to the hair follicles might be a significant event in the pathogenesis of early male pattern baldness. © 1989.
Klemp, P., Peters, K., & Hansted, B. (1989). Subcutaneous blood flow in early male pattern baldness. Journal of Investigative Dermatology, 92(5), 725–726. https://doi.org/10.1016/0022-202X(89)90189-9