Successful Pregnancy after Treatment with Ulipristal Acetate for Uterine Fibroids

  • Monleón J
  • Martínez-Varea A
  • Galliano D
  • et al.
N/ACitations
Citations of this article
23Readers
Mendeley users who have this article in their library.

Abstract

This case report presents a clinical pregnancy after ulipristal acetate (UA) to decrease uterine fibroid size. A 37-year-old patient, gravida 1, abortus 1, with uterine fibroids was treated with 5 mg of UA daily for 13 weeks starting eight months after a multiple laparotomic myomectomy. Fibroid shrinkage and restoration of the morphology of endometrial cavity were evaluated in order to allow a subsequent pregnancy. A decrease of the uterine fibroids and a normal morphology of the endometrial cavity were noted by transvaginal ultrasound after treatment. An endometrial biopsy excluded histologic endometrial changes. Three months after the end of UA the patient reported amenorrhea for 5 weeks and a clinical pregnancy was confirmed with transvaginal ultrasound. She underwent a subsequent uneventful pregnancy. Thus, the spontaneous pregnancy after UA to reduce fibroid size may support the potential clinical utility of this selective progesterone receptor modulator in the management of women with pregnancy desire and uterine fibroids after a prior myomectomy. Patients who refuse a new surgical procedure and/or those who are going to undergo assisted reproductive techniques would benefit from UA. It effectively shrinks fibroids, avoids risks of a new surgical procedure, and allows an immediate attempt at conception after the end of treatment.

Cite

CITATION STYLE

APA

Monleón, J., Martínez-Varea, A., Galliano, D., & Pellicer, A. (2014). Successful Pregnancy after Treatment with Ulipristal Acetate for Uterine Fibroids. Case Reports in Obstetrics and Gynecology, 2014, 1–3. https://doi.org/10.1155/2014/314587

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free