Surface antigens and potential virulence factors from parasites detected by comparative genomics of perfect amino acid repeats

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Abstract

Many parasitic organisms, eukaryotes as well as bacteria, possess surface antigens with amino acid repeats. Making up the interface between host and pathogen such repetitive proteins may be virulence factors involved in immune evasion or cytoadherence. They find immunological applications in serodiagnostics and vaccine development. Here we use proteins which contain perfect repeats as a basis for comparative genomics between parasitic and free-living organisms.<br />PMID: 18096064

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APA

Fankhauser, N., Nguyen-Ha, T. M., Adler, J., & Mäser, P. (2007). Surface antigens and potential virulence factors from parasites detected by comparative genomics of perfect amino acid repeats. Proteome Science, 5. https://doi.org/10.1186/1477-5956-5-20

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