Surface Properties Determining Passage Rates of Proteins through Nuclear Pores

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Abstract

Nuclear pore passage of proteins is surprisingly strongly affected by their surface amino acid composition, and this applies both to passive and receptor-mediated transport.

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Frey, S., Rees, R., Schünemann, J., Ng, S. C., Fünfgeld, K., Huyton, T., & Görlich, D. (2018). Surface Properties Determining Passage Rates of Proteins through Nuclear Pores. Cell, 174(1), 202-217.e9. https://doi.org/10.1016/j.cell.2018.05.045

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