Synapse formation requires the precise alignment and attachment of presynaptic and postsynaptic cells. Homophilic cell adhesion molecules have now been found to have a role in these processes on both sides of the synaptic cleft.
Abbas, L. (2003, January 8). Synapse formation: Let’s stick together. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)01384-2