Synthesis and antimicrobial activity of some new quinazolin-4(3H)-one derivatives

12Citations
Citations of this article
11Readers
Mendeley users who have this article in their library.

Abstract

A new series of 6-iodo-2-phenylquinazolin-4(3 H)-one derivatives was prepared and screened for antimicrobial activity. The thioureide derivatives 4- 6, the carbohydrazide derivatives 19- 21 and 24 displayed excellent broad-spectrum antimicrobial activity. Some compounds showed moderate activity against Candida albicans and Pseudomonas aeruginosa. None of the tested compounds was as active as the reference standard drugs ampicillin and clotrimazole. The detailed synthesis, antimicrobial activity, and the minimum inhibitory concentrations (MIC) are reported. © 2010.

Cite

CITATION STYLE

APA

Kadi, A. A. (2011). Synthesis and antimicrobial activity of some new quinazolin-4(3H)-one derivatives. Journal of Saudi Chemical Society, 15(2), 95–100. https://doi.org/10.1016/j.jscs.2010.06.001

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free