Synthesis, characterization and initial evaluation of 5-nitro-1- (trifluoromethyl)-3H-1λ3,2-benziodaoxol-3-one

17Citations
Citations of this article
17Readers
Mendeley users who have this article in their library.

Abstract

The synthesis of 5-nitro-1-(trifluoromethyl)-3H-1λ(3),2-benziodaoxol-3-one (3), a hypervalent-iodine-based electrophilic trifluoromethylating reagent, is described. Whereas considerations based on cyclic voltammetry and X-ray structural properties would predict an inferior reactivity when compared to the non-nitrated derivative 2, (19)F NMR kinetic studies showed that this new derivative is almost one order of magnitude more reactive. Furthermore, differential scanning calorimetry measurements indicated that, in addition, it is also safer to handle.

Cite

CITATION STYLE

APA

Santschi, N., Sarott, R. C., Otth, E., Kissner, R., & Togni, A. (2014). Synthesis, characterization and initial evaluation of 5-nitro-1- (trifluoromethyl)-3H-1λ3,2-benziodaoxol-3-one. Beilstein Journal of Organic Chemistry, 10, 1–6. https://doi.org/10.3762/bjoc.10.1

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free