Background: Environmental contamination with microorganisms is of growing concern in many healthcare facilities due to the risk of healthcare-associated infections. C difficile and A baumannii are two organisms that have shown increasing incidence in healthcare facilities and have extended resistance too many commonly used environmental disinfectants. Environmental contamination with these two organisms may therefore pose an infection risk to patients. Daily disinfection of the environment with chemicals capable of killing these organisms may reduce the bioburden of these organisms and decrease risk of transmission to subsequent patients. Objective: The objective of this study was to determine if daily disinfection of patient rooms is associated with decreased transmission of C difficile and A baumannii. Methods: We conducted an interventional study in a long-term acute care hospital in Louisville KY from September 1, 2011 through February 29, 2011. The first phase (September 1, 2011- November 30, 2011) utilized a one-step hypochlorite disinfectant (Clorox Dispatch) for daily cleaning and disinfection of all patient rooms housing patients known to be colonized or infected with either C difficile or A baumannii. The second phase (December 1, 2011- February 28, 2012) included cleaning and disinfection of all patient rooms in the facility. The Mid-P exact test was used to evaluate the difference in infection rates for both organisms from three months prior to the study and the interventional periods. No other infection prevention interventions were introduced during the study period. Results: For the three months prior to the start of the study, there were 14 cases of C difficile infection and 8,494 patient days. After the first three months of the intervention, there were 4 cases of C difficile and 8,140 patient days (P<0.001). There were 11 infections and 8,948 patient days for the second intervention period (P=0.111). For A baumannii infection, there were 33, 42, and 53 cases, respectively for the same numbers of patient days (P=0.224 and P=0.506). Conclusions: Targeted, daily disinfection with a one-step hypochlorite solution was effective at decreasing C difficile, but not A baumannii in the absence of other targeted infection prevention interventions.
T., W., A., F., J., C., R., C., & J., R. (2012). Targeted, daily environmental disinfection with clorox dispatch for the prevention of hospital-associated clostridium difficile and acinetobacter baumannii. American Journal of Infection Control. T. Wiemken, University of Louisville, School of Medicine, Division of Infectious Diseases, United States: Mosby Inc. Retrieved from http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed10&NEWS=N&AN=70811528