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Background: For Chlamydia trachomatis (CT), a test of cure (TOC) within 3-5 weeks is not recommended. International guidelines differ in advising a Neisseria gonorrhoeae (NG) TOC. Retesting CT and NG positives within 3-12 months is recommended in international guidelines. We assessed TOC and retesting practices including extragenital testing in general practitioner (GP) practices located in different socioeconomic status (SES) areas to inform and optimize local test practices. Methods: Laboratory data of 48 Dutch GP practices between January 2011 and July 2016 were used. Based on a patient's first positive CT or NG test, the proportion of TOC (<3 months) and retests (3-12 months) were calculated. Patient- and GP-related factors were assessed using multivariate logistic regression analyses. Results: For CT (n = 622), 20% had a TOC and 24% had a retest at the GP practice. GP practices in low SES areas were more likely to perform a CT TOC (OR:1.8; 95%CI:1.1-3.1). Younger patients (<25 years) were more likely to have a CT TOC (OR:1.6; 95%CI:1.0-2.4). For CT (n = 622), 2.4% had a TOC and 6.1% had a retest at another STI care provider. For NG (n = 73), 25% had a TOC and 15% had a retest at the GP practice. For NG (n = 73), 2.7% had a TOC and 12.3% had a retest at another STI care provider. In only 0.3% of the consultations patients were tested on extragenital sites. Conclusion: Almost 20% of the patients returned for a CT TOC, especially at GP practices in low SES areas. For NG, 1 out of 4 patients returned for a TOC. Retesting rates were low for both CT (24%) and NG (15%), (re)infections including extragenital infections may be missed. Efforts are required to focus TOC and increase retesting practices of GPs in order to improve CT/NG control.




J.N.A.P., W., G.A.F.S., V. L., C.J.P.A., H., J.W.L., C., P.F.G., W., & N.H.T.M., D.-M. (2018). Test of cure, retesting and extragenital testing practices for Chlamydia trachomatis and Neisseria gonorrhoeae among general practitioners in different socioeconomic status areas: A retrospective cohort study, 2011-2016. PLoS ONE, 13(3). https://doi.org/10.1371/journal.pone.0194351 LK  - http://resolver.ebscohost.com/openurl?sid=EMBASE&issn=19326203&id=doi:10.1371%2Fjournal.pone.0194351&atitle=Test+of+cure%2C+retesting+and+extragenital+testing+practices+for+Chlamydia+trachomatis+and+Neisseria+gonorrhoeae+among+general+practitioners+in+different+socioeconomic+status+areas%3A+A+retrospective+cohort+study%2C+2011-2016&stitle=PLoS+ONE&title=PLoS+ONE&volume=13&issue=3&spage=&epage=&aulast=Wijers&aufirst=Julien+N.A.P.&auinit=J.N.A.P.&aufull=Wijers+J.

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