The "test Your Memory" test performs better than the MMSE in a population without known cognitive dysfunction

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Abstract

Aim To examine the relation of performance on the self-administered Test Your Memory test (TYM) and the Mini-Mental State Examination (MMSE) with a comprehensive neuropsychological assessment in a population sample including people with modest cognitive decrements. Methods Eighty-six participants (aged 56-77 years), without known cognitive dysfunction, performed a neuropsychological assessment including MMSE, and were asked to fill out the TYM. The relation between both the TYM and the MMSE and a neuropsychological assessment was examined by means of correlation analyses, area under the ROC curves for discriminating between a "normal" and "modest decrements"(≥ 1SD below the sample mean) group, and Bland-Altman plots. Results Correlation with the full neuropsychological assessment was significantly stronger for the TYM than the MMSE (r = 0.78 versus r = 0.55; Steiger's Z = 2.66, p < 0.01). The TYM showed an area under the ROC-curve of 0.88 (95% CI 0.80 to 0.97) for differentiating between "normal" and "modest decrements" compared with 0.71 (0.53 to 0.90) for the MMSE. Bland-Altman plots showed limits of agreement for the TYM of - 1.10 to 1.10 and for the MMSE of - 1.39 to 1.38. Conclusions The TYM showed good correlation with a neuropsychological assessment, performed better in discriminating between variations of cognition and showed more agreement with a neuropsychological assessment than the MMSE. © 2013 Elsevier B.V.

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Koekkoek, P. S., Rutten, G. E. H. M., Van Den Berg, E., Van Sonsbeek, S., Gorter, K. J., Kappelle, L. J., & Biessels, G. J. (2013). The “test Your Memory” test performs better than the MMSE in a population without known cognitive dysfunction. Journal of the Neurological Sciences, 328(1–2), 92–97. https://doi.org/10.1016/j.jns.2013.02.028

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