The study investigated functional associations between left hemisphere occipitotemporal, temporoparietal, and inferior frontal regions during oral pseudoword reading in 58 school-aged children with typical reading skills (aged 10.4 ± 1.6, range 7.5-12.5. years). Event-related neuromagnetic data were used to compute source-current density waveforms using a minimum norm algorithm. Temporally-constrained contributions were established for four ROIs (STG, SMG, ANG, and IFG) by controlling for the autoregressive effects of activity in each ROI. Unique contributions made by activity in one ROI to subsequent activity in a second ROI were assessed through multiple regression analyses. Forward associations between lateral (LOC) and ventral occipitotemporal cortices (fusiform gyrus) to each of the four main ROIs were also examined. The earliest significant contributions to SMG and ANG activation (at 200-250. ms) were made by preceding activity in the fusiform gyrus. The degree of activity in IFG appeared to be determined by earlier activity in ANG and STG. © 2012 Elsevier Inc.
Simos, P. G., Rezaie, R., Fletcher, J. M., & Papanicolaou, A. C. (2013). Time-constrained functional connectivity analysis of cortical networks underlying phonological decoding in typically developing school-aged children: A magnetoencephalography study. Brain and Language, 125(2), 156–164. https://doi.org/10.1016/j.bandl.2012.07.003