Toward clinically compatible phase-contrast mammography

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Abstract

© 2015 Scherer et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Phase-contrast mammography using laboratory X-ray sources is a promising approach to overcome the relatively low sensitivity and specificity of clinical, absorption-based screening. Current research is mostly centered on identifying potential diagnostic benefits arising from phase-contrast and dark-field mammography and benchmarking the latter with conventional state-of-the-art imaging methods. So far, little effort has been made to adjust this novel imaging technique to clinical needs. In this article, we address the key points for a successful implementation to a clinical routine in the near future and present the very first dosecompatible and rapid scan-time phase-contrast mammograms of both a freshly dissected, cancer-bearing mastectomy specimen and a mammographic accreditation phantom.

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Scherer, K., Willer, K., Gromann, L., Birnbacher, L., Braig, E., Grandl, S., … Pfeiffer, F. (2015). Toward clinically compatible phase-contrast mammography. PLoS ONE, 10(6). https://doi.org/10.1371/journal.pone.0130776

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