Toxin detection by surface plasmon resonance

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Abstract

Significant efforts have been invested in the past years for the development of analytical methods for fast toxin detection in food and water. Immunochemical methods like ELISA, spectroscopy and chromatography are the most used in toxin detection. Different methods have been linked, e.g. liquid chromatography and mass spectrometry (LC-MS), in order to detect as low concentrations as possible. Surface plasmon resonance (SPR) is one of the new biophysical methods which enables rapid toxin detection. Moreover, this method was already included in portable sensors for on-site determinations. In this paper we describe some of the most common methods for toxin detection, with an emphasis on SPR. © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

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Hodnik, V., & Anderluh, G. (2009). Toxin detection by surface plasmon resonance. Sensors, 9(3), 1339–1354. https://doi.org/10.3390/s9031339

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