The TriTryp phosphatome: Analysis of the protein phosphatase catalytic domains

Citations of this article
Mendeley users who have this article in their library.


The genomes of the three parasitic protozoa Trypanosoma cruzi, Trypanosoma brucei and Leishmania major are the main subject of this study. These parasites are responsible for devastating human diseases known as Chagas disease, African sleeping sickness and cutaneous Leishmaniasis, respectively, that affect millions of people in the developing world. The prevalence of these neglected diseases results from a combination of poverty, inadequate prevention and difficult treatment. Protein phosphorylation is an important mechanism of controlling the development of these kinetoplastids. With the aim to further our knowledge of the biology of these organisms we present a characterisation of the phosphatase complement (phosphatome) of the three parasites.




Brenchley, R., Tariq, H., McElhinney, H., Szöor, B., Huxley-Jones, J., Stevens, R., … Tabernero, L. (2007). The TriTryp phosphatome: Analysis of the protein phosphatase catalytic domains. BMC Genomics, 8.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free