TRPML and lysosomal function

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Abstract

Mucolipin 1 (MLN1), also known as TRPML1, is a member of the mucolipin family. The mucolipins are the only lysosomal proteins within the TRP superfamily. Mutations in the gene coding for TRPML1 result in a lysosomal storage disorder (LSD). This review summarizes the current knowledge related to this protein and the rest of the mucolipin family. © 2007 Elsevier B.V. All rights reserved.

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Zeevi, D. A., Frumkin, A., & Bach, G. (2007, August). TRPML and lysosomal function. Biochimica et Biophysica Acta - Molecular Basis of Disease. https://doi.org/10.1016/j.bbadis.2007.01.004

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