The chaperone/usher pathway is responsible for the assembly of adhesive pili on the surface of gram-negative pathogenic bacteria. In this issue, Remaut et al. (2008) present the crystal structure of the PapC usher translocation domain and images of the FimD usher bound to a pilus translocation intermediate. These new structures provide the first detailed view of a translocase in action. © 2008 Elsevier Inc. All rights reserved.
Daniels, R., & Normark, S. (2008, May 16). Twin Ushers Guide Pili across the Bacterial Outer Membrane. Cell. https://doi.org/10.1016/j.cell.2008.04.032