Usefulness of an abnormal ankle-brachial index for detecting multivessel coronary disease in patients with acute coronary syndrome | Utilidad de un índice tobillo-brazo patológico en la identificación de la enfermedad coronaria multivaso en pacientes con

  • Núñez D
  • Morillas P
  • Quiles J
  • et al.
N/ACitations
Citations of this article
1Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Introduction and objectives: The presence of peripheral arterial disease in patients with coronary artery disease is associated with a poor cardiovascular outcome. However, the majority of affected patients are asymptomatic and the condition is underdiagnosed. The ankle-brachial index (ABI) provides a simple method of diagnosis. The aim of this study was to assess the usefulness of an abnormal ABI for identifying multivessel coronary artery disease in patients with acute coronary syndrome (ACS). Methods: We analyzed data on all ACS patients included in the PAMISCA multicenter study (with 94 participating hospitals) who underwent catheterization during admission. Patients were diagnosed with multivessel coronary disease if two or more major epicardial vessels or the left main coronary artery, or both, were affected. An ABI ≤0.9 or >1.4 was considered abnormal. Results: The study included 1031 patients with a mean age of 67.7 years. Of these, 542 had multivessel disease (52.6%). Compare with those without multivessel disease, these patients were older (66.6 years vs. 62.6 years; P<.001), had higher prevalences of hypertension (65.9% vs. 56.2%; P<.005), diabetes mellitus (40.6% vs. 26.0%; P<.001) and hypercholesterolemia (89.1% vs. 80.4%; P<.001), and were more likely to have a history of cardiovascular disease (30.1% vs. 13.9%; P<.001) or an abnormal ABI (45.4% vs. 30.3%; P<.001). Multivariate analysis showed that the presence of an abnormal ABI was associated with an increased risk of multivessel disease (odds ratio=1.58; 95% confidence interval, 1.16-2.15; P<.05). Conclusions: In patients with ACS, an abnormal ABI was independently associated with the risk of multivessel coronary artery disease.

Cite

CITATION STYLE

APA

Núñez, D., Morillas, P., Quiles, J., Cordero, A., Guindo, J., Soria, F., … Bertomeu, V. (2010). Usefulness of an abnormal ankle-brachial index for detecting multivessel coronary disease in patients with acute coronary syndrome | Utilidad de un índice tobillo-brazo patológico en la identificación de la enfermedad coronaria multivaso en pacientes con . Revista Espanola de Cardiologia, 63(1). https://doi.org/10.1016/S0300-8932(10)70009-9

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free