Variability in uremic control during continuous venovenous hemodiafiltration in trauma patients

4Citations
Citations of this article
7Readers
Mendeley users who have this article in their library.

Abstract

Introduction. Acute kidney injury (AKI) necessitating continuous renal replacement therapy (CRRT) is a severe complication in trauma patients (TP). We wanted to assess daily duration of CRRT and its impact on uremic control in TP. Material and Methods. We retrospectively reviewed adult TP, with or without rhabdomyolysis, with AKI undergoing CRRT. Data on daily CRRT duration and causes for temporary stops were collected from the first five CRRT days. Uremic control was assessed by daily changes in serum urea (Δ urea) and creatinine (Δ creatinine) concentrations. Results. Thirty-six TP were included with a total of 150 CRRT days, 17 (43%) with rhabdomyolysis. The median (interquartile range (IQR)) time per day with CRRT was 19 (15-21) hours. There was a significant correlation between daily CRRT duration and Δ urea (r=0.60, P≤0.001) and Δ creatinine (r=0.43; P=0.012). CRRT pauses were caused by filter clotting (54%), therapeutic interventions (25%), catheter related problems (10%), filter timeout (6%), and diagnostic procedures (6%). Rhabdomyolysis did not affect the CRRT data. Conclusions. TP undergoing CRRT had short daily CRRT duration causing reduced uremic control. Clinicians should modify their daily clinical practice to improve technical skills and achieve sufficient dialysis dose. © 2012 Sigrid Beitland et al.

Cite

CITATION STYLE

APA

Beitland, S., Sunde, K., Moen, H., & Os, I. (2012). Variability in uremic control during continuous venovenous hemodiafiltration in trauma patients. Critical Care Research and Practice, 2012. https://doi.org/10.1155/2012/869237

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free