Recent data have found that Plasmodium ovale can be separated in two distinct species: classic and variant P. ovale based on multilocus typing of different genes. This study presents a P. ovale isolate from a patient infected in Ghana together with an analysis of the small subunit RNA, cytochrome b, cytochrome c oxidase I, cysteine protease and lactate dehydrogenase genes, which show that the sample is a variant P. ovale and identical or highly similar to variant P. ovale isolated from humans in South-East Asia and Africa, and from a chimpanzee in Cameroon. The split between the variant and classic P. ovale is estimated to have occurred 1.7 million years ago. © 2011 Tordrup et al; licensee BioMed Central Ltd.
Tordrup, D., Virenfeldt, J., Andersen, F. F., & Petersen, E. (2011). Variant Plasmodium ovale isolated from a patient infected in Ghana. Malaria Journal, 10. https://doi.org/10.1186/1475-2875-10-15