In this issue of the Journal, Fathi et al. (1) describe the value of measuring vasomotor endothelial dysfunction and intima medial thickness of the far wall of the common carotid artery as predictors of clinical outcome in patients at risk for cardiovascular events. This adds to a growing-but-small list of publications exploring this important theme, but in contrast to most of the previous literature, the authors suggest that endothelial dysfunction does not add independent prognostic information when considered in the context of other test results.
Mancini, G. B. J. (2004, February 18). Vascular structure versus function: Is endothelial dysfunction of independent prognostic importance or not? Journal of the American College of Cardiology. Elsevier USA. https://doi.org/10.1016/j.jacc.2003.11.017