Venlafaxine-induced REM sleep behavioral disorder presenting as two fractures

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Rapid eye movement (REM) sleep behavioral disorder is characterized by the absence of muscular atonia during REM sleep. In this disorder, patients can violently act out their dreams, placing them at risk for traumatic fractures during these episodes. REM sleep behavioral disorder (RBD) can be a sign of future neurodegenerative disease and has also been found to be a side effect of certain psychiatric medications. We present a case of venlafaxine-induced RBD in a 55 year old female who presented with a 13 year history of intermittent parasomnia and dream enactment in addition to a recent history of two fractures requiring intervention.




Ryan Williams, R., & Sandigo, G. (2017). Venlafaxine-induced REM sleep behavioral disorder presenting as two fractures. Trauma Case Reports, 11, 18–19.

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