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killed the beadle/tatum hypothesis; destroyed genomic reductionism; disposed the gene concept; built a 4 dimensional integrated model of life interfaced with the envir. across time; established the ubiquitous misuse of correlation coefficients (correlation implies neither causation nor concordance); demonstrated extreme biases from pcr; showed pcr efficacy at amplifying attomoles of nucleic acid; abolished the relationship between transcript copy and protein quantity; documented methodological relativism.

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