1,7-Electrocyclisation of non-stabilised azomethine ylides

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Abstract

Non-stabilised α,β,γ,δ-unsaturated azomethine ylides 3 were generated by the decarboxylation method from 3,3-diarylpropenals 1 and secondary amino acids 2. 1,7-Electrocyclisation of these azomethine ylides, followed by a 1,5-hydrogen shift, gives 2,3-dihydro-1H-2-benzazepines 4.

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Arany, A., Groundwater, P. W., & Nyerges, M. (1998). 1,7-Electrocyclisation of non-stabilised azomethine ylides. Tetrahedron Letters, 39(20), 3267–3268. https://doi.org/10.1016/S0040-4039(98)00466-3

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