A 500-MHz1H-n.m.r. study of oligosaccharides derived from gangliosides by ozonolysis-alkaline fragmentation

  • Dorland L
  • van Halbeek H
  • Vliegenthart J
 et al. 
  • 4

    Readers

    Mendeley users who have this article in their library.
  • 16

    Citations

    Citations of this article.

Abstract

The structural-reporter-group resonances in the1H-n.m.r. spectra of a series of ganglioside-derived oligosaccharides are completely assigned. The three different types of sialic acid residues which may occur in these compounds could be adequately characterized. They are distinguishable on the basis of the set of chemical shifts of their H-3a and H-3e atoms. The mutual influence of GalNAc β-(1→4) and Neu5Ac α-(2→3), both linked to the same Gal residue, on the1H-n.m.r. parameters of each other, reflects a well-defined solution confirmation, which is held to be responsible for the resistance of this "internal" sialic acid towards various sialidases. © 1986.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Lambertus Dorland

  • Herman van Halbeek

  • Johannes F G Vliegenthart

  • Roland Schauer

  • Herbert Wiegandt

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free