Actin

Abstract

Actin is one of the most important proteins that build the cytoskeleton and nucleoskeleton of a eukaryotic cell. It is a conserved protein, the most abundant in the cell, and it has the ability to polymerize and forms complexes with other proteins. It can undergo mutations in human organisms, usually they are missense mutations, causing systemic diseases. It correlates with a very large number of other proteins. In the human body, it is coded by 6 genes and has many important functions that enable it to function properly. Very important function performed by nuclear actin is the structure of the nucleoskeleton and the control of transcription. It was first discovered in the 19th century.