Active F-transport: Species and age effects with rodent intestine, in vitro

  • Parkins F
  • 3

    Readers

    Mendeley users who have this article in their library.
  • 4

    Citations

    Citations of this article.

Abstract

Active F-transport in a secretory direction across everted sacs of intestinal sections from four species of rodents was observed. Both the F-specific electrode and microdiffusion methods of fluoride analysis were employed. 1. 1. Net accumulation of F-in the mucosal fluid of ileal sacs was observed in three of the four species studied. Sacs from gerbil and hamster exhibited the greater rates of active F-transport. 2. 2. Active F-transport with gerbil ileum exhibited a unilateral dependency on the presence of Cl-in the mucosal compartment, as had previously been reported for rat, suggesting that the mechanism was similar. 3. 3. A decrease in active F-transport was observed within the age range of 4-18 weeks with both rat and gerbil ileal sacs. 4. 4. F-secretion by active transport was also observed in sacs of jejunum and colon from gerbil, as had previously been reported for rat, confirming that the process occurs along the entire length of rodent intestine. © 1971.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • Frederick M. Parkins

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free