Adenine dinucleotide-mediated cytosolic free Ca2+ oscillations in single hepatocytes

  • Green A
  • Dixon C
  • McLennan A
 et al. 
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Abstract

Single rat hepatocytes microinjected with aequorin respond to Ca2+-mobilizing agonists, including ADP and ATP, with oscillations in cytosolic free Ca2+. We show here that single rat hepatocytes also respond to the adenine dinucleotides Ap3A and Ap4A with Ca2+oscillations which resemble those induced by ADP and ATP. © 1993.

Author-supplied keywords

  • Adenine dinucleotide
  • Ca2+oscillation
  • Purinoceptor
  • Single hepatocyte

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Authors

  • Anne K. Green

  • C. Jane Dixon

  • Alexander G. McLennan

  • Peter H. Cobbold

  • Michael J. Fisher

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